Acute PFOA exposure promotes epigenomic alterations in mouse kidney tissues
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چکیده
منابع مشابه
Radiation and cadmium induced biochemical alterations in mouse kidney
Background: In the present investigation radiation and cadmium induced biochemical changes in the kidney of Swiss albino mice have been studied. Materials and Methods: For this purpose, adult male Swiss albino mice (6-8 weeks old) were divided into four groups. Group I (sham-irradiated), Group II (treated with CdCl2 solution 20 ppm), Group III (irradiated with 1.25, 2.5 and 5.0 Gy gamma rays), ...
متن کاملradiation and cadmium induced biochemical alterations in mouse kidney
background: in the present investigation radiation and cadmium induced biochemical changes in the kidney of swiss albino mice have been studied. materials and methods: for this purpose, adult male swiss albino mice (6-8 weeks old) were divided into four groups. group i (sham-irradiated), group ii (treated with cdcl2 solution 20 ppm), group iii (irradiated with 1.25, 2.5 and 5.0 gy gamma rays), ...
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Functional and structural abnormalities in the renal microvasculature are important processes contributing to the pathophysiology of ischemic acute kidney injury (AKI). In this study, we examine the contribution of endothelial cell loss via apoptosis on microvascular permeability and rarefaction in a mouse model of ischemic AKI. Three-dimensional reconstructions of microvascular networks obtain...
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Prostate cancer (PC) is the second most frequently diagnosed cancer and the second leading cause of cancer deaths in man. The treatment of localized PC includes surgery or radiation therapy. In case of relapse after a definitive treatment or in patients with locally advanced or metastatic disease, the standard treatment includes the androgen-deprivation therapy (ADT). By reducing the levels of ...
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Although the biokinetics, metabolism, and chemical toxicity of methyl tert-butyl ether are well known, little attention was paid to the potential toxic effects of MTBE on reproduction and development in mammals. To evaluate the effects of MTBE on pregnant animals, two groups (control and test) of NMRI mice were chosen. In test group 500 and 1000 mg/Kg of it were administered intraperitonealy at...
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ژورنال
عنوان ژورنال: Toxicology Reports
سال: 2020
ISSN: 2214-7500
DOI: 10.1016/j.toxrep.2019.12.010